Canadian-Australasian Randomised Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease
The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER waitlist activation is not inferior to regular (i.e., annual) screening for CAD during wait-listing for the prevention of Major Adverse Cardiac Events. Secondary analyses will assess the impact of screening on the rate of transplantation, and the relative cost-effectiveness of screening.
• adults aged 18 years of age or older
• Dialysis-dependent kidney failure and currently being assessed for OR active on the kidney transplant waiting list
• expected to require further screening for CAD prior to transplantation (by current standard of care);
• able to give consent;
• anticipated to undergo transplantation more than 12 months from date of enrolment